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Brain2Vec: A Self-Supervised 3D Foundation Model for Structural Brain MRI

Spiros Maggioros, Guray Erus, Gareth Harman, George Aidinis, Alexander Getka, Aristeidis Sotiras, Christos Davatzikos · 2026 · arXiv

DOI: 10.48550/arXiv.2610.28411 · open-access PDF

Chinese

深度学习模型已成为医疗成像的必不可少工具,但由于有限的标记数据和计算限制,为各种任务提供端到端培训仍然具有挑战性。 为了解决这一问题,我们介绍了Brain2Vec,一个基于74425 T1计量磁共振成像(MRI)扫描的基础模型,从多个研究中组合起来。

Machine translation (Meta M2M100); the English original follows.

Abstract

Deep learning models have become essential tools in medical imaging, yet training them end-to-end for diverse tasks remains challenging due to limited labeled data and computational constraints. To address this, we introduce Brain2Vec, a foundation model pre-trained on 74,425 T1-weighted Magnetic Resonance Imaging (MRI) scans pooled from multiple studies. Brain2Vec can serve both as a weight initialization backbone for fine-tuning downstream tasks and as a standalone feature extractor. We evaluated Brain2Vec in three tasks: downstream predictive performance, convergence speed, and embedding qu

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