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Reference Manual of MEDiml

Mahdi Ait Lhaj Loutfi, Simon Provost, Elodie Gillard, Moustafa Amine Bezzahi, Alexander Chum, Ben Coull-Nveu, Duran Juan, Mariem Kallel, Hakima Laribi, Oliver Lefebvre, Nicolas Longchamps, Thanh-Tri Nguyen, Steven Ravary, Ouael Nedjem Eddine Sahbi, Jérémy Dana, Martin Vallières · 2026 · arXiv (Cornell University)

DOI: 10.48550/arxiv.2610.29666 · cited by 0 works (OpenAlex) · open-access PDF

Portuguese

Este trabalho de composição de componentes é a extração de alta potência de características quantitativas (por exemplo, forma de tumor, distribuições de intensidade e textura) a partir de imagens médicas para caracterizar tecidos e descobrir padrões complexos de doença invisíveis ao olho humano. Esses recursos podem servir como biomarcadores de imagem candidatos para diagnóstico de câncer, prognóstico e classificação. No entanto, extrair milhares de características torna difícil identificar os mais informativos para uma determinada tarefa clínica, enquanto a implementação de um fluxo de trabalho complexo end-to-end pode exigir especialização em programação que limite a acessibilidade para pesquisadores clínicos de texto. Portanto, propomos MEDiml, uma plataforma de biomarcadores baseada em código aberto, compatível com padrões radiométricos que conecta a extração de

Machine translation (Meta M2M100); the English original follows.

Abstract

Radiomics is the high-throughput extraction of quantitative features (e.g., tumor shape, intensity distributions, and texture) from medical images to characterize tissues and uncover disease patterns invisible to the human eye. These features can serve as candidate imaging biomarkers for cancer diagnosis, prognosis, and classification. However, extracting thousands of features makes it difficult to identify the most informative ones for a given clinical task, while implementing an end-to-end workflow can require programming expertise that limits accessibility for clinical researchers. Hence, we propose MEDiml, an open-source, standards-compliant radiomics platform connecting feature extraction, predictive modeling, and interpretation through complementary graphical and programmatic interfaces. MEDiml combines a Python package (MEDiml-pkg) with a graphical desktop application (MEDiml-app) that enables researchers to conduct experiments without writing code. Both interfaces use the same computational implementation, and code generation exports graphically configured workflows as executable Python code, facilitating reproducibility and collaboration between clinical researchers and computational scientists. A typical MEDiml workflow includes image preprocessing, radiomic feature extraction, feature set reduction, model training and evaluation, and interpretation using feature importance. Feature sets can be grouped into levels of radiomic complexity (morphological, intensity-based, textural, and filter-based) to evaluate whether more complex features provide additional predictive value. This reference manual documents the radiomics concepts, workflow, software components, architecture, and installation, compares MEDiml with existing tools, and demonstrates its complexity-driven workflow on five oncological imaging cohorts comprising 2,104 patients. Resources: www.mediml.app.

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Topics: Workflow, Python (programming language), Computer science, Executable, Feature (linguistics), Software

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