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Diffusion-Based Synthesis of Complete 3D Biparametric Prostate MRI

Claudia Giardina, Montse Pardàs, Verónica Vilaplana · 2026 · arXiv

DOI: 10.48550/arXiv.2610.31523 · open-access PDF

Abstract

Synthetic biparametric MRI (bpMRI) may help alleviate the limited availability of large and representative prostate MRI datasets for deep learning applications. In this work, we present a conditional 3D diffusion framework for anatomy-conditioned synthesis of complete prostate bpMRI from anatomical masks. The framework supports sequential synthesis, in which T2w and diffusion modalities are generated by separately trained models, and joint synthesis, in which all bpMRI modalities are generated simultaneously within a single model. Five configurations were trained using PI-CAI, FastMRI Prostate

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