Newest papers

An Open Reliability Atlas of Sensitivity and Failure Modes in the Pulse Physiology Engine

Santino Nanini, Arnaud Wiedemann, Yassir Mamouni, Cyril Schweitzer, Philippe A. Jouvet, Michael Sauthier · 2026 · arXiv (Cornell University)

DOI: 10.48550/arxiv.2610.28517 · cited by 0 works (OpenAlex) · open-access PDF

Chinese

Pulse 是一个积极维护的开源成人生理学模拟器,但其维护者没有报告其运营输入的正式敏感性分析。我们在其关键护理包装中展示了第一个开放的可靠性亚特拉斯:Morris elementary-effects 采样七个输入,四个严重性场景,男性和女性身体 (1,280 个模拟) 敏感性被扭曲:三个输入携带每个输出总量的中位数为 93% 一个四旗分类器揭示了失败模式:两个操作员可操作的,一个性分层化。Tidal 体积振动 (20.6% 的运行)与病人风扇失调一致;锁定 VCAC 触发器到 -2 H2O 厘米导致这种变量崩溃。在 FiO2 = 1.0,

Machine translation (Meta M2M100); the English original follows.

Abstract

Pulse is an actively maintained open-source adult-physiology simulator, yet its maintainers report no formal sensitivity analysis of its operational inputs. We present the first open reliability atlas across its critical-care envelope: Morris elementary-effects sampling of seven inputs, four severity scenarios, male and female bodies (1,280 simulations). Sensitivity is skewed: three inputs carry a median 93% of each output's total. A four-flag classifier reveals failure modes: two operator-actionable, one sex-stratified. Tidal-volume oscillation (20.6% of runs) is consistent with patient-ventilator dyssynchrony; locking the VC-AC trigger to -2 cmH2O collapses that variability. At FiO2 = 1.0, transient hyperoxia makes 120-second runs underestimate plateau PaO2; 300-second healthy-lung reruns give a median 643 mmHg. Solver divergence was all-male in an input-extreme regime (20/1,280); reducing the male blood-volume baseline to the 4,082 mL floor eliminated it. Runs and flags are released openly, showing users which regions need checking before training on Pulse output.

Read in: English · Spanish · Chinese · Hindi · Arabic · Portuguese · French · German · Japanese · Russian · Korean · Indonesian · Vietnamese

Topics: Computer science, Sensitivity (control systems), Atlas (anatomy), Pulse (music), Reliability (semiconductor), Acoustics

Sources: OpenAlex (CC0), arXiv, Crossref. Agent Exchange